Drug Information
- Brand : Tadapox;
- Active substance : Tadalafil/Dapoxetine;
- Manufacturer : Centurion Laboratories.
Tadapox and its active substances Tadalafil/Dapoxetine
The new drug combination Tadapox (Tadalafil/Dapoxetine) has become a real breakthrough in the treatment of sexual dysfunction. The pharmacological action is due to two active substances, each with a different mechanism of action, but designed to improve sexual function.
Tadalafil works by increasing the activity of one of the chemicals (nitric oxide) that the body releases into the penis during sexual arousal. As a result of this action, a number of biochemical and hemodynamic changes occur:
- The three arteries of the penis are dilated;
- Blood flow is increased (blood flow is temporarily restricted);
- The corpus spongiosum and two corpora cavernosa of the penis are filled with blood;
- The penis increases in size (the phase of full and hard erection is reached).
The mechanism of action of Dapoxetine is related to an increase in the level and activity of serotonin in the CNS. High serotonin activity in the brain leads to:
- Improved ejaculation control;
- The increase in the time it takes to ejaculate.
Indications for use
Tadapox is used for the treatment of various problems related to male sexual function:
- Premature ejaculation;
- Weak erection after sexual arousal;
- Weakening of erection during sexual intercourse;
- Complete inability to achieve an erection.
The drug is prescribed for various types of the above disorders, including psychogenic, organic or mixed disorders.
Treatment regimens and dosages
This medication comes in the form of tablets for oral use. There is only one dosage form of Tadapox available on the market. Each Tadapox tablet contains 20 mg of tadalafil + 60 mg of dapoxetine.
The standard dosage regimen of Tadapox for adults:
- The safe daily dose is 80 mg (1 tablet);
- Take one tablet at least 30 to 60 minutes before sexual intercourse;
- Take Tadapox 1-3 hours before if you want to be 100% ready for sex.
To achieve an erection while taking Tadapox, any form of sexual stimulation is necessary. This medication does not cause sexual desire and does not affect male libido.
Recommendations for use
For best results with Tadapox and guaranteed elimination of sexual dysfunction, follow these recommendations:
- Do not take the tablets more than once a day;
- Do not chew or crush the tablets, take them whole;
- Take Tadapox 80 mg with a large glass of water;
- Do not use the medicine after a fatty meal, as this may delay its effect.
Tadapox 80 mg can only be taken once a day, as the effect of dapoxetine lasts for about 10 to 12 hours and the effect of tadalafil can last up to 36 hours.
Missed dose
Take one dose of Tadapox 80 mg as needed before intercourse, not more than once a day.
Precautions
Before taking Tadapox, it is better to consult a doctor, if you have or have ever had health problems such as:
- Severe depression;
- Heart attack or stroke within the past six months;
- Moderate or severe liver disease;
- Severe valvular heart disease;
- Optic neuropathy.
Do not take alcohol with Tadapox, as it may cause increased dizziness, drowsiness, blurred vision, etc.
Use of Tadapox during pregnancy
Tadapox is not intended for the treatment of female sexual dysfunction. It should not be taken by women, including those who are pregnant or breastfeeding.
Possible side effects
The following side effects are relatively common when using Tadapox:
- Insomnia;
- Drowsiness;
- Headache;
- Redness of the face;
- Tinnitus.
At the same time, none of these effects are mild and do not cause serious complications. After a few days of regular use of Tadapox, the side effects disappear.
Tadalafil and Dapoxetine: interaction with other drugs
Important information: If you are taking Tadapox 80 mg or any other medication for erectile dysfunction, never use nitrates (vasodilators). This can cause a significant drop in blood pressure, hypotensive crisis, and coma.
Various types of interactions (not always serious) may occur if you use this medicine with:
- Drugs acting on the central nervous system (hypnotics, antipsychotics, antidepressants, etc.);
- Antifungals such as ketoconazole (Nizoral) or itraconazole (Lozanoc);
- Antiretroviral drugs such as Ritonavir (Norvir, Kaletra).
Storage
Store in a dry place at room temperature between 15°C and 25°C. Exposure to ultraviolet rays, humidity, or heat may impair the therapeutic properties of the drug.
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