Medication Information
- Brand: Tadapox;
- Active substance: Tadalafil/Dapoxetine;
- Manufacturer: Centurion Laboratories.
Tadapox and its active substances Tadalafil/Dapoxetine
The new drug combination Tadapox (Tadalafil/Dapoxetine) has become a real breakthrough in the treatment of sexual dysfunctions. The pharmacological action is due to two active substances, each with a different mechanism of action, but both aim to improve sexual function.
Tadalafil works by increasing the activity of one of the chemicals (nitric oxide) that the body releases into the penis during sexual arousal. As a result of this action, a certain amount of biochemical and hemodynamic changes occur:
- The three arteries of the penis dilate;
- Blood flow is increased (blood outflow is temporarily restricted);
- The corpus spongiosum and two corpora cavernosa of the penis fill with blood;
- The penis increases in size (the phase of a full and hard erection is reached).
Dapoxetine's mechanism of action is linked to an increase in serotonin levels and activity in the CNS. High serotonin activity in the brain leads to:
- Improved ejaculation control;
- Increased time to ejaculate.
Indications for use
Tadapox is used for the treatment of various problems related to male sexual function:
- Premature ejaculation;
- Weak erection after sexual arousal;
- Weakening of erection during sexual intercourse;
- Complete inability to get an erection.
The medication is prescribed for various types of the above disorders, including psychogenic, organic, or mixed disorders.
Treatment regimens and dosages
This medication comes in tablet form for oral use. There is only one dosage form of Tadapox available on the market. Each Tadapox tablet contains 20 mg of tadalafil + 60 mg of dapoxetine.
The standard adult dosing regimen for Tadapox:
- The safe daily dose is 80 mg (1 tablet);
- Take one tablet at least 30 to 60 minutes before sexual intercourse;
- Take Tadapox 1-3 hours before if you want to be 100% ready for sex.
To achieve an erection when taking Tadapox, some form of sexual stimulation is necessary. This medication does not cause sexual desire and does not affect male libido.
Recommendations for use
For best results with Tadapox and guaranteed elimination of sexual dysfunction, follow these recommendations:
- Do not take tablets more than once a day;
- Do not chew or crush tablets, take them whole;
- Take Tadapox 80 mg with a large glass of water;
- Do not use the medication after a fatty meal, as this may delay its effect.
Tadapox 80 mg can only be taken once a day, as the effect of dapoxetine lasts approximately 10-12 hours and the effect of tadalafil can last up to 36 hours.
Missed dose
Take a dose of Tadapox 80 mg as needed before sexual intercourse, no more than once a day.
Precautions
Before taking Tadapox, it is best to consult a doctor if you have or have had health problems such as:
- Severe depression;
- Heart attack or stroke within the last six months;
- Moderate or severe liver disease;
- Severe valvular heart disease;
- Optic neuropathy.
Do not drink alcohol with Tadapox, as this may cause increased dizziness, drowsiness, blurred vision, etc.
Use of Tadapox during pregnancy
Tadapox is not intended for the treatment of female sexual dysfunctions. It should not be taken by women, including those who are pregnant or breastfeeding.
Possible side effects
The following side effects are relatively common when using Tadapox:
- Insomnia;
- Drowsiness;
- Headache;
- Facial flushing;
- Tinnitus.
At the same time, none of these effects are severe and do not cause serious complications. After a few days of regular Tadapox use, side effects disappear.
Tadalafil and Dapoxetine: interaction with other medications
Important information: If you are taking Tadapox 80 mg or any other erectile dysfunction medication, never use nitrates (vasodilators). This can lead to a significant drop in blood pressure, a hypotensive crisis, and coma.
Various types of interactions (not always serious) may occur if you use this medication with:
- Medications acting on the central nervous system (hypnotics, antipsychotics, antidepressants, etc.);
- Antifungals such as ketoconazole (Nizoral) or itraconazole (Lozanoc);
- Antiretroviral drugs such as Ritonavir (Norvir, Kaletra).
Storage
Store in a dry place at room temperature between 15°C-25°C. Exposure to ultraviolet rays, moisture, or heat can impair the therapeutic properties of the medication.
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