Clomid (Clomiphene)

Drug Information

• Brand: Clomid;
• Active ingredient: Clomiphene Citrate;
• Manufacturer: Sanofi, Pacifique, Bruno Pharma.

Active ingredient Clomiphene

Clomiphene was approved for medical use in 1967. It is a drug in the category of ovulation inducers, listed by WHO.

Clomiphene has a pronounced antiestrogenic effect.

Estrogen plays an important role in the conception process. This hormone:

• Stimulates the secretion of cervical mucus (the favorable environment necessary for the life, movement and nutrition of sperm);
• Stimulates the release of luteinizing hormone (LH);
• Promotes regeneration and growth of the endometrium.

Estrogen deficiency or excess can lead to the inability of ovulation, and therefore of pregnancy.

Clomiphene provides a unique therapeutic effect. It does not directly affect the concentration of estrogen in the blood, but affects estrogen receptors, which themselves regulate the level of the hormone.

In case of estrogen deficiency, these receptors increase their activity, while they decrease their activity with excess estrogen.

Clomid only helps create the conditions for a natural change in estrogen levels in the female body. Therefore, it is not a hormone replacement therapy drug and does not have any negative effects on the female body.

Under the influence of the drug, the concentration of luteinizing and follicle-stimulating hormones temporarily increases in the female body.

This effect usually lasts for 5 days, after which the concentration of these hormones decreases. However, with a probability of more than 76%, one or more follicles appear and mature, leading to an increase in estrogen concentration, thus ultimately causing a surge of LH and ovulation in the middle of the cycle.

Directions for use

Clomid is prescribed for pathologies caused by the imbalance of female sex hormones in the body, such as:

• Absence of menstruation – amenorrhea;
• Periods too rare – oligomenorrhea;
• Dysfunctional uterine bleeding;
• Milky discharge from the nipple not related to breastfeeding – galactorrhea;
• Low sperm count in men – oligospermia;
• Male breast enlargement – ​​gynecomastia.

As the indications show, Clomid is also recommended for men who have increased estrogen levels. In the male body, it acts in the same way and helps reduce the level of female sex hormones and increase testosterone.

Ways to Buy Clomid

Clomid is a prescription drug sold at most pharmacies in the city. You can consult your doctor, get tested, get a prescription, and buy pills at a pharmacy near you.

But this isn't always the best method. You'll have to pay for the doctor's consultation, and Clomid tablets will be quite expensive at a local pharmacy. They can be at least three times more expensive than at an online pharmacy.

You can also buy Clomid in our online pharmacy, but at a much lower price. Minimizing the cost of maintaining an online resource and direct supplies from the manufacturer make the online price of Clomid the most suitable for most people with low or middle incomes. We ensure that every customer of our pharmacy has access to affordable medications and can take care of their health without limitations.

Please compare the prices yourself and you will see that buying Clomid online at our pharmacy is more cost-effective and will not affect your budget.

Treatment regimens and dosages

To successfully treat anovulatory infertility, Clomid is used in 5-day cycles/steps for 1-6 months (depending on the rate of ovulation).

The first stage of treatment begins on the 5th day of the menstrual cycle. Take one 50 mg Clomid tablet daily for 5 days. After stopping the tablets, you should check for ovulation. It can occur 7-18 days after the end of treatment. If this does not occur, it is best to repeat the treatment.

For the second and subsequent stages of treatment, the Clomid dose should be increased to 100 mg per day. The regimen is repeated: start treatment on the 5th day of the menstrual cycle and continue for 10 days. The increased duration of treatment is necessary for longer control of estrogen receptors.

Clomid 100 mg tablets are taken for at least 2-4 cycles to assess the effectiveness of the drug and identify comorbidities affecting the possibility of conception.

Men with oligospermia are advised to start treatment with the minimum daily dose of Clomid 25 mg.

The tablets are taken 2-3 times a day for 3-4 months. If the spermogram parameters do not show positive dynamics after a month of treatment, the dosage can be increased to 50 mg, 2-3 times a day. The total daily dose should not exceed 150 mg.

Recommendations for use

Please note that treatment starts with a minimal dose to test tolerance to Clomiphene.

• The tablets are taken daily, regardless of food, intake without missing a single dose.
• It is very important to start taking the pills from the 5th day of the menstrual cycle – neither later nor earlier.
• If menstruation is absent, start treatment any day.

To determine the effectiveness of Clomid, after each treatment cycle, transvaginal ultrasound is necessary to check the development of follicles.

If ovulation does not occur, the treatment is repeated.

Missed dose

You should not miss a single dose of Clomid. If you miss a dose, you must restart the entire course of treatment from scratch. Taking a double or triple dose will not make any difference and can cause side effects. Therefore, it is important to follow the dosage schedule carefully.

Precautions

The use of Clomid is strictly contraindicated with the following diagnoses:

• Severe liver/kidney failure;
• Uterine bleeding of unknown origin;
• Tumors in the pituitary gland;
• Pathological dysfunctions of the pituitary gland;
• Endometriosis.

Using Clomid during pregnancy

Clomid is used to improve reproductive function in both males and females. However, it should not be used during pregnancy. Using the drug during pregnancy can cause miscarriage and termination of the pregnancy.

It is also advisable to avoid using the drug during breastfeeding.

Possible side effects

The most common side effect of Clomid is reversible ovarian enlargement in women. This effect is natural due to increased levels of female sex hormones, so it won't cause much discomfort.

Less common symptoms include headache, hot flashes, abdominal discomfort/pain.

Very rarely (in less than 1% of patients), taking Clomid can cause liver inflammation, changes in blood count, and uterine bleeding.

Doctors also include the possibility of multiple ovulations and the likelihood of conceiving twins or triplets as side effects. However, this is not often the case.

Clomid: interaction with other drugs

Due to the specific mechanism of pharmacological action, Clomiphene does not interact with most known drugs. Treatment is carried out without specific limitations for this reason.

We just need to remind you that during treatment:

• You should give up alcohol;
• You should not take two drugs with a similar effect at the same time, for example, Clomid and Tamoxifen;
• You can use additional gonadotropic hormone medications.

Storage

Store in a dark place, out of reach of children, at a temperature not exceeding 25°C.

How to buy Clomid online?

Our online pharmacy's pricing policy is designed for the widest range of consumers. Even if you have a low income, this doesn't mean you have to deprive yourself.

Our goal is to maintain reproductive health. Ultimately, our employees do everything they can to ensure that every woman and man has the opportunity to buy Clomid at a low price and never give up hope of having a child.

We offer our clients:

• Prices below market;
• 24/7 technical support;
• Fast delivery to your home;
• Total security and anonymity of each order.

By buying Clomid online, you have the opportunity to make your dream come true and have a child.